Occurrence and uses Pyrazole



celecoxib, pyrazole derivative used analgesic


in 1959, first natural pyrazole, 1-pyrazolyl-alanine, isolated seeds of watermelons.


in medicine, derivatives of pyrazoles used analgesic, antinociceptive, anti-inflammatory, antipyretic, antiarrhythmic, tranquilizing, muscle relaxing, analeptic, anticonvulsant, monoamineoxidase inhibiting, antidiabetic, antifungal, , antibacterial activities.


the pyrazole ring found within variety of pesticides fungicides, insecticides , herbicides, including chlorfenapyr, fenpyroximate, fipronil, tebufenpyrad, tolfenpyrad, , tralopyril.








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